Research Article

Evaluation of Hepatoprotective Activity of Caralluma europaea Stem Extract against CCl4-Induced Hepatic Damage in Wistar Rats

Table 3

Effect of aqueous extract of Caralluma europaea on CCl4-induced kidney function test in serum.

Treatment (n = 6)Creatinin (mg/mL)Urea (g/L)Uric acid (mg/L)

Normal control5.763 ± 0.130.593 ± 0.0311.883 ± 1.46
CCl4 only (1 mL/kg )5.857 ± 0.24ns0.648 ± 0.05ns9.600 ± 1.04ns
AECe (250 mg/kg) + CCl45.737 ± 0.11ns0.521 ± 0,05ns8.467 ± 0.46ns
AECe only (250 mg/kg)5.941 ± 0.23ns0.671 ± 0.0411.633 ± 0.98
CCl4 + silymarin (40 mg/kg)5.757 ± 0.110.558 ± 0.02ns10.180 ± 0.27ns

Data expressed in mean ± SEM (n = 6) and analyzed with one-way ANOVA followed by Tukey’s test. The meaning was compared with the normal control group. ns = not significant.