Research Article
In Silico, In Vitro, and In Vivo Wound Healing Activity of Astragalus microcephalus Willd.
Table 2
Flavonoids present in the extract and their affinity to binding to the ERs α and β.
| Ligand | ER α (Kcal/mol) | ER β (Kcal/mol) |
| Estradiol | −7.7 to −6.7 | −7.5 to −6.4 | Finasteride | −7 to −6.8 | −8.2 to −6.6 | Formononetin | −7.2 to−6.4 | −8 to −6.2 | Kaempferol-3-O-glucoside | −7.9 to −6.9 | −8.5 to −7.1 | Kaempferol-3-O-sophoroside | −7.4 to −6.7 | −8.0 to −7.4 | Kaempferol-3-O-neohesperidoside | −7.9 to −7.3 | −7.3 to −6.8 | Quercetin-3-O-neohesperidoside | −7.8 to −6.8 | −7.9 to−7.3 | Calycosin-7-O-beta-D-glucoside | −7.6 to −7 | −7.7 to −7.2 |
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Molecular docking results indicated that all ligands had a high affinity (<−6.3) to receptors.
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