Research Article
Antidiabetic Properties and Toxicological Assessment of Antidesma celebicum Miq: Ethanolic Leaves Extract in Sprague–Dawley Rats
Table 6
Relative organ weight of experimental animals after 14 days of single oral administration of different doses of EEAC from acute toxicity study.
| Sex | Dose (mg/kg BW) | Relative organ weight (g/kg) | Liver | Kidney (R) | Kidney (L) | Heart | Spleen | Lung |
| Male | 0 | 35.98 ± 0.96 | 3.55 ± 0.12 | 3.80 ± 0.13 | 3.19 ± 0.15 | 2.23 ± 0.09 | 4.99 ± 0.23 | 300 | 35.34 ± 3.41 | 3.68 ± 0.42 | 3.70 ± 0.48 | 3.17 ± 0.42 | 2.58 ± 0.14 | 6.64 ± 0.51 | 2000 | 34.10 ± 1.25 | 4.08 ± 0.18 | 4.08 ± 0.18 | 3.03 ± 0.11 | 2.74 ± 0.15 | 6.61 ± 0.33 | 5000 | 35.26 ± 1.96 | 3.42 ± 0.25 | 3.39 ± 0.22 | 3.19 ± 0.21 | 2.56 ± 0.13 | 6.44 ± 0.95 |
| Female | 0 | 36.35 ± 2.32 | 3.47 ± 0.21 | 3.55 ± 0.16 | 3.46 ± 0.05 | 2.45 ± 0.07 | 5.66 ± 0.31 | 300 | 33.43 ± 2.47 | 3.25 ± 0.30 | 3.25 ± 0.30 | 2.72 ± 0.29 | 2.53 ± 0.18 | 5.84 ± 0.54 | 2000 | 37.38 ± 1.73 | 3.27 ± 0.24 | 3.45 ± 0.26 | 2.91 ± 0.16 | 2.67 ± 0.18 | 6.56 ± 0.83 | 5000 | 33.80 ± 2.79 | 3.60 ± 0.20 | 3.69 ± 0.17 | 2.99 ± 0.10 | 2.67 ± 0.18 | 9.98 ± 3.36 |
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Data are expressed as Mean ± SEM ( n = 5). Significantly different from control group was designated as . |