Passiflora mollissima Seed Extract Induced Antiproliferative and Cytotoxic Effects on CAL 27 Spheroids

Figure 3

Dose-response curve of effects on cell viability of CAL 27 spheroid treated with PME. The spheroids were treated with three extract concentrations (10, 50, and 100 μg/ml) and 20 μM cisplatin. (a) Viability percent of spheroids treated. Each bar represents the median and interquartile range of 7 independent experiments for 72 h evaluation times. (b) Comparison between viability percentages monolayer and three-dimensional cultures are shown (p < 0.005).

(a)

(b)