Passiflora mollissima Seed Extract Induced Antiproliferative and Cytotoxic Effects on CAL 27 Spheroids

Figure 7

The inhibitory effects of PME and Cisplatin on cell colony formation in CAL 27 spheroids. (a) Representative dishes by colony-forming assay (b) Inhibitory effect of PME (10, 50, and 100 μg/ml) and cisplatin 20 μM on cell proliferation in CAL-27 spheroids and the influence of oral cancer cells on the number of colony-forming cells at 72 hours. The results shown are representative of three independent experiments. p < 0.05, control versus PME-treated cells.

(a)

(b)