Evaluation of Dermal Toxicity and Wound Healing Activity of Cnestis ferruginea Vahl ex DC
Table 6
Haematological parameters for the toxicity test.
Test
Control
CFM
250 mg/kg
value
500 mg/kg
value
1000 mg/kg
value
RBCs (106/μL)
8.10 ± 0.6
8.12 ± 0.5
>0.99
8.0 ± 1.1
0.99
7.94 ± 1.1
>0.96
HB (g/dL)
14.5 ± 1.2
14.3 ± 1.1
0.97
13.9 ± 1.6
0.61
13.8 ± 1.3
0.50
HCT (%)
47.2 ± 1.1
47.2 ± 0.6
>0.99
46.9 ± 1.2
0.93
47.5 ± 2.1
0.93
MCV (μm3)
58.3 ± 2.3
58.3 ± 3.3
>0.99
58.1 ± 1.0
0.99
57.1 ± 1.6
0.42
MCH (pg)
17.6 ± 0.7
18.2 ± 0.1
0.58
17.4 ± 1.2
0.97
17.2 ± 2.1
0.82
MCHC (g/dL)
30.7 ± 1.4
30.7 ± 1.4
>0.99
29.9 ± 1.0
0.41
32.4 ± 1.5
0.79
Platelets (103/μL)
836 ± 14.1
835 ± 14.1
0.99
843 ± 12.1
0.54
864 ± 15.2
0.04
WBCs (103/μL)
9.4 ± 3.1
9.4 ± 3.2
>0.99
8.78 ± 0.9
0.96
8.9 ± 5.3
0.98
RBCs: red blood cells, HB: haemoglobin, HCT: haematocrit, MCV: mean corpuscular volume, MCH: mean corpuscular haemoglobin, MCHC: mean corpuscular haemoglobin concentration, WBCs: white blood cells. Level of significance: values expressed as mean ± SEM, n = 10 (one-way ANOVA).
