Phytochemical Analysis and Antifungal Potentiating Activity of Extracts from Loquat (Eriobotrya japonica) against Cryptococcus neoformans Clinical Isolates

Table 2

Antifungal activity of E. japonica extracts and antifungals against clinical isolates of C. neoformans.

Extracts	Isolates
	CN		CN169		CN173		CN047		CN091		CN165		CN118		CN046		CN096		CN158
	MIC	MFC	MIC	MFC	MIC	MFC	MIC	MFC	MIC	MFC	MIC	MFC	MIC	MFC	MIC	MFC	MIC	MFC	MIC	MFC
HeS	512	-	1024	-	512	-	1024	-	256	-	512	-	64	256	1024	-	256	-	512	-
ChS	1024	-	1024	-	1024	-	512	-	512	-	1024	-	512	-	512	-	1024	-	1024	-
EaS	1024	-	512	-	1024	-	64	256	1024	-	1024	-	256	-	256	1024	512	-	512	-
MeS	1024	-	512	-	512	-	32	128	512	-	256	1024	512	-	128	512	128	1024	512	-
HeL	1024	-	512	-	1024	-	512	-	256	512	32	256	32	128	32	128	256	512	128	256
ChL	256	-	512	-	1024	-	1024	-	1024	-	512	-	256	512	1024	-	512	-	1024	-
EaL	512	-	1024	-	1024	-	1024	-	512	-	1024	-	1024	-	512	-	1024	-	512	-
MeL	512	-	512	-	1024	-	256	-	1024	-	512	-	1024	-	256	-	512	-	512	-
HeB	1024	-	1024	-	1024	-	512	-	512	-	512	-	1024	-	512	-	1024	-	1024	-
ChB	1024	-	512	-	1024	-	1024	-	512	-	512	-	512	-	1024	-	512	-	1024	-
EaB	512	-	256	1024	256	512	256	1024	128	512	1024	-	1024	-	512	-	512	-	1024	-
MeB	512	-	128	512	1024	-	1024	-	256	1024	1024	-	512	-	256	512	128	512	512	-
Nystatin	8	8	32	256	16	32	4	8	8	128	16	64	4	8	32	128	4	8	4	8
Clotrimazole	16	64	32	128	2	8	2	16	2	16	8	32	4	32	4	32	4	16	2	16

−, >1024 µg/mL for extracts; HeS, hexane extract of seed; ChS, chloroform extract of seed; EaS, ethyl acetate extract of seed; MeS, methanol extract of seed; HeL, hexane extract of leaves; ChL, chloroform extract of leaves; EaL, ethyl acetate extract of leaves; MeL, methanol extract of leaves; HeB, hexane extract of bark; ChB, chloroform extract of bark; EaB, ethyl acetate extract of bark; MeB, methanol extract of bark. Bold values represent significant antifungal activity.