In Vitro and In Vivo Antiproliferative Actions of Solanum gilo Raddi (Solanaceae) Fruit Extract on Breast Tissues

Figure 4

Effects of S. gilo hydroethanolic extract on microphotographs H and E 400× of liver, kidney, lung, and brain after 16 weeks of treatment. NOR = Normal control treated with distilled water; E2V = E2V-control treated with distilled water; SG + E2V = Animals treated with the S. gilo hydroethanolic extract at the doses of 125, 250, and 500 mg/kg BW. TAMOX + E2V = Animals treated with tamoxifen (3.3 mg/kg BW); all groups except the normal group (NOR) received chronic administration of E2V at the dose of 1 mg/kg BW. Data are represented as mean ± SEM (n = 6). Vp = Veine portal; H = Hepatocyte; S = Sinusoids; Py = Pyknotic nuclei; A = Alveoli; Ab = Aveolar bag; G = Glomerula; Dt = Distal tube; Pt = Proximal tube; Mi = Microglie; Ne = Neurone; Co = Cortex.