Biological Activity and Chemical Composition of Detarium microcarpum Guill. and Perr—A Systematic Review

Table 9

Anticancer activity of D. microcarpum.

S/N	Method	Solvents	Part of the plant	Major findings	Reference
9	Presto blue cell viability assay	Methanol and aqueous	Stem bark	The IC50 values for the methanol and aqueous extracts of the three plants inhibiting MCF7 cell growth ranged from 78 to >500 μg/mL. The strongest antioxidant and antiproliferative activity was observed in stem bark extracts. As a result, the stem bark of these plants may contain anti-breast cancer chemicals.	[59]
		Aqueous	Leaf and stem	The leaf extracts inhibited the cancer cell, the percentage inhibition increased as well, reaching 89.47% optimal dosage of 100 mg/cm^3. However, this research has revealed leaf’s promise as a cancer therapeutic, particularly in developing nations, and has brought new knowledge to science.	[88]
		Aqueous	dAgNps (leaves)	HeLa cell growth was decreased by dAgNps with IC50 values of 31.5 μg/mL.	[79]

Notes: S/N = serial number.