In Vitro Antioxidant, Anti-Inflammatory, and Digestive Enzymes Inhibition Activities of Hydro-Ethanolic Leaf and Bark Extracts of Psychotria densinervia (K. Krause) Verdc

Table 5

IC₅₀ and correlation coefficient (r) of hydro-ethanolic leaf and bark extracts in lipase, cholesterol esterase, α-amylase, and α-glucosidase inhibition activity compared to standards.

Enzymes	Parameters	Inhibitors
		Standards	Bark	Leaf
Lipase	IC50 (μg/ml)	37.11 ± 4.39	62.88 ± 1.74	50.57 ± 2.89^†
	R^2	0.9908	0.9931	0.9641
Cholesterol esterase	IC50 (μg/ml)	54.61 ± 2.56	80.14 ± 1.71	34.75 ± 3.87^†
	R^2	0.9938	0.9949	0.9945
α-Amylase	IC50 (μg/ml)	20.01 ± 2.84	19.69 ± 6.27	6.06 ± 4.05^†
	R^2	0.9967	0.9903	0.9953
α-Glucosidase	IC50 (μg/ml)	4.11 ± 3.47	38.81 ± 2.46	24.41 ± 2.84^†
	R^2	0.9898	0.9979	0.9949

Data are expressed as mean ± SD, n = 3; significantly different at when compared to standards (orlistat) in lipase and cholesterol esterase inhibition tests; acarbose in α-amylase and α-glucosidase inhibition test). ^† compared to bark extract.