Review Article

Advancement of Nanofibrous Mats and Common Useful Drug Delivery Applications

Table 2

Representative drugs loaded into electrospun mats for drug delivery applications.

Nanofibrous matDrugApplicationReferences

ChitosanBromelainBurn wound recovery[24]
GelatinDoxycyclineSkin wound dressing[28]
Graphene oxideTetracycline hydrochlorideWound dressings[29]
Chitosan-alginateGentamicinSkin wound dressing[30]
Hyaluronic acid and silk fibroinZinc oxideWound dressings and antibacterial patch[31]
PolycaprolactoneVancomycinBone healing[33]
PolydopamineMetronidazoleAnti-infection agent[34]
PolycaprolactoneLinezolid and oxazolidinoneSkeletal prosthetic limb pathogens[35]
Galactomannan polymerLevofloxacin hydrochlorideAntibacterial tablets[36]
Polyethylene glycolDoxorubicinAnticancer[41]
Polycaprolactone (ethylene glycol)Doxorubicin and apatinibAnticancer[42]
Poly-L-lactic acid5-FU-K-PAnticancer[43]
Polyvinyl chlorideDoxorubicinAnticancer[44]
ChitosanThiocarbonyl groupsAnticancer[45]
PolycaprolactoneCarvedilolCardiovascular diseases[51]
Poly-L-lactic acidDipyridamoleAntithrombotic[52]
ChitosanSimvastatinPrevention of arteries narrowing[53]
PolycaprolactoneCilostazolPrevent strokes[54]
Polycaprolactone and Pluronic 123CilostazolPrevent strokes[55]
Poly (lactic-co-glycolic acid)PirfenidoneCorneal abrasion[61]
Gellan gum/pullulanMoxifloxacinTopical ocular infection[62]
PolyvinylpyrrolidoneFerulic acidHemorrhage[63]
PolycaprolactoneInterfering RNAInterfering RNA release[70]
Polycaprolactone and polyethylene phosphateInterfering RNAInterfering RNA and transfection[71]
Alginate sulfate and polyvinyl alcoholTransforming growth factor-beta 1Transforming growth factor-beta 1 release[72]
Poly (D,L-lactic acid)Nerve growth hormoneNerve growth hormone release[73]