Review Article
Advancement of Nanofibrous Mats and Common Useful Drug Delivery Applications
Table 2
Representative drugs loaded into electrospun mats for drug delivery applications.
| Nanofibrous mat | Drug | Application | References |
| Chitosan | Bromelain | Burn wound recovery | [24] | Gelatin | Doxycycline | Skin wound dressing | [28] | Graphene oxide | Tetracycline hydrochloride | Wound dressings | [29] | Chitosan-alginate | Gentamicin | Skin wound dressing | [30] | Hyaluronic acid and silk fibroin | Zinc oxide | Wound dressings and antibacterial patch | [31] | Polycaprolactone | Vancomycin | Bone healing | [33] | Polydopamine | Metronidazole | Anti-infection agent | [34] | Polycaprolactone | Linezolid and oxazolidinone | Skeletal prosthetic limb pathogens | [35] | Galactomannan polymer | Levofloxacin hydrochloride | Antibacterial tablets | [36] | Polyethylene glycol | Doxorubicin | Anticancer | [41] | Polycaprolactone (ethylene glycol) | Doxorubicin and apatinib | Anticancer | [42] | Poly-L-lactic acid | 5-FU-K-P | Anticancer | [43] | Polyvinyl chloride | Doxorubicin | Anticancer | [44] | Chitosan | Thiocarbonyl groups | Anticancer | [45] | Polycaprolactone | Carvedilol | Cardiovascular diseases | [51] | Poly-L-lactic acid | Dipyridamole | Antithrombotic | [52] | Chitosan | Simvastatin | Prevention of arteries narrowing | [53] | Polycaprolactone | Cilostazol | Prevent strokes | [54] | Polycaprolactone and Pluronic 123 | Cilostazol | Prevent strokes | [55] | Poly (lactic-co-glycolic acid) | Pirfenidone | Corneal abrasion | [61] | Gellan gum/pullulan | Moxifloxacin | Topical ocular infection | [62] | Polyvinylpyrrolidone | Ferulic acid | Hemorrhage | [63] | Polycaprolactone | Interfering RNA | Interfering RNA release | [70] | Polycaprolactone and polyethylene phosphate | Interfering RNA | Interfering RNA and transfection | [71] | Alginate sulfate and polyvinyl alcohol | Transforming growth factor-beta 1 | Transforming growth factor-beta 1 release | [72] | Poly (D,L-lactic acid) | Nerve growth hormone | Nerve growth hormone release | [73] |
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