Pharmacometrics: A New Era of Pharmacotherapy and Drug Development in Low- and Middle-Income Countries

Table 1

Advantages of pharmacometrics.

Subjects	Areas	Particulars
Pharmacometrics	Clinical drug development	To inform and optimize dose selection
		To inform route of administration, bioequivalence, and formulation decisions
		To help determine the route of administration of drugs
		To quantify exposure-response relationships for efficacy and safety and subsequent clinical utility
		To help repurposing of the drug
	Pharmacotherapy practice	To optimize the drug dosage regimen in special patient populations such as pediatrics, geriatrics, pregnancy, lactating women, genetically different patient populations, and patients with renal and liver impairment
		To optimize and individualize dosing to ensure optimal efficacy and safety