Pharmacometrics: A New Era of Pharmacotherapy and Drug Development in Low- and Middle-Income Countries
Table 1
Advantages of pharmacometrics.
Subjects
Areas
Particulars
Pharmacometrics
Clinical drug development
To inform and optimize dose selection
To inform route of administration, bioequivalence, and formulation decisions
To help determine the route of administration of drugs
To quantify exposure-response relationships for efficacy and safety and subsequent clinical utility
To help repurposing of the drug
Pharmacotherapy practice
To optimize the drug dosage regimen in special patient populations such as pediatrics, geriatrics, pregnancy, lactating women, genetically different patient populations, and patients with renal and liver impairment
To optimize and individualize dosing to ensure optimal efficacy and safety