Investigating the Presence of Falsified and Poor-Quality Fixed-Dose Combination Artemether-Lumefantrine Pharmaceutical Dosage Forms in Kumasi, Ghana

Table 4

Quality tests for fixed-dose AL tablets.

Samples	Diameter (mm)  SD	Thickness (mm)  SD	Hardness (kg/mm^2)  SD	^ΨFriability (%)	^¥Disintegration time (min)  SD
LZT	16.49 ± 0.33	5.67 ± 0.10	5.43 ± 1.11	0.11	13 ± 0.13
LNT	12.05 ± 0.09	5.94 ± 0.09	7.00 ± 0.85	0.01	5 ± 0.24
MLT	19.18 ± 0.07	6.85 ± 0.10	8.52 ± 0.52	0.02	4 ± 0.05
LFT	12.57 ± 0.60	5.81 ± 0.11	4.34 ± 1.23	0.66	2 ± 0.11
CTT	20.24 ± 0.04	5.86 ± 0.08	8.40 ± 0.67	0.05	2 ± 0.03
TMT	18.46 ± 0.06	5.81 ± 0.11	5.62 ± 0.58	0.15	5 ± 0.18
IDT	21.13 ± 0.11	5.68 ± 0.09	7.58 ± 0.95	0.18	12 ± 0.01
DMT	16.49 ± 0.33	5.67 ± 0.10	6.92 ± 0.57	0.50	3 ± 0.16

Acceptance criteria (BP) = 4–10 kg/mm². ^ΨAcceptance criteria (BP) = NMT 1%. ^¥Acceptance criteria (BP) = NMT 15 minutes.