Research Article

In Vitro Antibacterial, DPPH Radical Scavenging Activities, and In Silico Molecular Modeling of Isolated Compounds from the Roots of Clematis hirsuta

Table 4

Bacterial growth inhibition zone of extracts and isolated compounds.

Test sampleConcentration (mg/mL)Inhibition zone in mm (mean ± SD)
S. aureusS. pyogenesE. coliP. aeruginosa

MeOH extract1008.20 ± 0.1212.30 ± 0.219.20 ± 0.129.30 ± 0.22
50NI8.20 ± 0.127.20 ± 0.12NI

n-hexane: EtOAc (1 : 1) extract10011.20 ± 0.1310.30 ± 0.258.40 ± 0.2615.20 ± 0.17
507.10 ± 0.138.30 ± 0.13NI10.20 ± 0.12

3511.10 ± 0.1710.50 ± 0.2110.30 ± 0.2410.60 ± 0.55
2.57.27 ± 0.558.70 ± 0.228.20 ± 0.178.20 ± 0.17

559.07 ± 0.128.80 ± 0.179.10 ± 0.199.10 ± 0.12
2.5NINI7.60 ± 0.13NI

6510.10 ± 0.1010.20 ± 0.1710.40 ± 0.2910.20 ± 0.22
2.58.27 ± 0.467.50 ± 0.228.30 ± 0.168.40 ± 0.24

Ciprofloxacin0.518.42 ± 0.2619.93 ± 0.2120.00 ± 0.2122.18 ± 0.22

Note. NI: no inhibition.