In Vitro Antibacterial, DPPH Radical Scavenging Activities, and In Silico Molecular Modeling of Isolated Compounds from the Roots of Clematis hirsuta

Table 9

Drug-likeness predictions of isolated compounds computed by SwissADME.

Ligand	Formula	MWT (g/mol)	NRB	NHA	NHD	TPSA ()	Log P	Lipinski’s rule of five
3	C29H48O	412.7	5	1	1	20.2	7.0	1
4	C29H50O	414.7	6	1	1	20.2	6.73	1
5	C40H40O12	712.7	17	12	3	159.4	5.4	2
6	C40H42O13	730.8	20	13	4	179.4	5.3	2
Ciprofloxacin	C17H18FN3O3	331.3	3	5	2	74.6	−1.1	0
Abiraterone	C24H31NO	349.5	1	2	1	33.1	4.4	1 (MLogP > 4.15)

Note. MWT: molecular weight; NRB: number of rotatable bonds; NHA: number of hydrogen acceptors; NHD: number of hydrogen donors; TPSA: total polar surface area.