Suppression of Inflammation in Adipocyte-Macrophage Coculture by Passion Fruit Seed Extract: Insights into the p38 and NF-ҡB Pathway

Figure 5

Suppression of NF-κB and p38MAPK signaling pathways by PSEE in LPS-induced inflammation in cocultured adipocytes and macrophages. (a) Western blot analysis of NF-κB, ERK1/2, and p38MAPK protein bands in response to PSEE treatment. (b) Relative expression of p-p38/p38 protein. (c) Relative expression of pERK/ERK protein. (d) Relative expression of NF-κB protein. All values are expressed as the mean ± SEM from four independent experiments (n = 4). Statistical significance was determined using LSD post-hoc analysis, with significance accepted when (# compared to the control group and compared to the LPS group).

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