Functional Glycopolypeptides: Synthesis and Biomedical Applications

Figure 3

(a) Schematic pathways for the preparation of glycopolypeptide analogues via a combination of RAFT polymerization, NCA ring-opening polymerization, and “click” coupling reaction; (b) TEM images for the PMAgala₂₇-SS-PBLG₃₀ self-assembled micelles; (c) galactose competitive inhibition experiments to show HepG2-targeting effects. Fluorescence microscopic images (400x) of HepG2 cells were pretreated with C6-loaded micelles (100 μg/mL) under galactose of various concentrations.

(a)

(b)

(c)