3D In Vitro Human Organ Mimicry Devices for Drug Discovery, Development, and Assessment

Figure 11

(a) Schematic diagram of the alveolar structure. (b) Schematic diagram of microfluidic chip with PLGA nanofiber membrane as substrate prepared by electrospinning. (c) Schematic diagram of culture of A549 cells on the chip. (d) Schematic diagram of the coculture of A549 cells and HFL1 cells. (e) Schematic diagram of the coculture of A549 cells, HFL1 cells, and HUVECs. Reproduced (or adapted) with permission [73], ©2018, Royal Society of Chemistry.

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