3D In Vitro Human Organ Mimicry Devices for Drug Discovery, Development, and Assessment

Figure 14

Fabrication of the primary human intestine chip. (a) A schematic microdevice showing the upper epithelium (blue), the lower microvascular cells (pink), and the porous membrane in-between. The different microfluidic channels and some components are shown. (b) Schematic representation of the procedure involved in the establishment of microfluidic cocultures (epithelium and endothelium). Reproduced (or adapted) with permission [87], ©2018, Nature.

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