Nuclear-Targeting Delivery of CRISPRa System for Upregulation of β-Defensin against Virus Infection by Dexamethasone and Phenylalanine Dual-Modified Dendrimer

<div>Confocal laser scanning microscopy (CLSM) images of human kidney 293T cells (a), mouse neuroblastoma N2a cells (b), and human lung adenocarcinoma A549 cells (c) incubated with Lipo2000/plasmid, G4 (Phe)25%/plasmid, G4 (Phe)50%/plasmid, and G4 (Phe)50%-DET/plasmid. Incubation time: 48 h. Nuclei: stained blue with DAPI; green fluorescence: EGFP protein. Scale bars represent 100 μm.</div>

Advances in Polymer Technology

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Figure 5

Figure 5: Nuclear-Targeting Delivery of CRISPRa System for Upregulation of β-Defensin against Virus Infection by Dexamethasone and Phenylalanine Dual-Modified Dendrimer

Figure 5 | Nuclear-Targeting Delivery of CRISPRa System for Upregulation of β-Defensin against Virus Infection by Dexamethasone and Phenylalanine Dual-Modified Dendrimer 