Ganoderma lucidum Polysaccharide (GLP) Inhibited the Progression of Oral Squamous Cell Carcinoma via the miR-188/BCL9/β-Catenin Pathway

Figure 6

miR-188 regulated the β-catenin pathway by targeting BCL9. (a) BCL9 and miR-188 binding sites were predicted on the microRNA.org website; (b) verification of the binding sites via the luciferase reporter gene experiment; (c) miR-188 regulates BCL9 and nuclear β-catenin expression; (d and e) miR-188 regulates mRNA and protein expression of β-catenin downstream genes. ^∗P < 0.05

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