Review Article
Archaeal Nucleic Acid Ligases and Their Potential in Biotechnology
Table 2
Properties of archaeal RNA ligases.
| Organism | UniProt ID | PDB ID | Co-Factor | | Properties | Reference |
| Pyrococcus abyssi | Q9UYG2 | 2VUG | ATP | 85–90°C | Efficient at forming adenylated RNA but not so efficient at strand joining. Forms circular products. | [62] |
| Methanothermobacter thermautotrophicus | O27289 | — | ATP | 65°C | Circularises single-stranded RNA and single-stranded DNA. | [63] |
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: temperature optimum for the RNA ligase in vitro.
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