|
| # | Drug (dose in mg/kg/inj) | Alternative reinforcer | Species | Main effect examined | Ref. |
|
| 1 | Cocaine (0.05–0.1) | Cocaine (0.013–0.8) | Rhesus | Effect of drug dose | [9] |
| 2 | Cocaine (0.05–0.1) | Cocaine (0.05–0.1) | Rhesus | Effect of schedule type
| [30] |
| 3 | Cocaine (0.05 or 0.1) | Cocaine (0.013–0.8) | Rhesus | Effect of drug dose
| [34] |
| 4 | Cocaine (0.025–0.2) | Cocaine (0.025–0.2) | Rhesus | Effects of dose and schedule manipulations
| [33] |
| 5 | Cocaine (0.03–0.3) | Cocaine (0.03–0.3) | Rhesus | Effect of infusion delay
| [32] |
| 6 | Cocaine (0.025–0.05) | Cocaine (0.025–0.05)
Food pellet
| Rhesus | Effect of reinforcement delay
| [37] |
| 7 | Cocaine (0.05–0.2) | Cocaine (0.05–0.2) | Rhesus | Effect of reinforcement probability
| [38] |
| 8 | Cocaine (0.025–0.1) | Cocaine (0.025–0.1) | Rhesus | Application of generalized matching law
| [40] |
| 9 | Cocaine (0.025–0.1) | Cocaine (0.025–0.1) | Rhesus | Effect of schedule type
| [39] |
| 10 | Cocaine (0.1–0.75) | Cocaine (0.1–0.75) | Rhesus | Effect of punishment (electric shock)
| [71] |
| 11 | Cocaine (0.3–1) | Cocaine (0.3–1) | Rat | Effect of infusion rate
| [35] |
| 12 | Nicotine (0.015) | Nicotine (0.015) | Rat | Effect of infusion rate | [36] |
| 13 | Cocaine (0.05)
Alfentanil (0.001–0.004)
Methohexital (0.25–0.5) | Cocaine (0.05)
Alfentanil (0.001–0.004)
Methohexital (0.25–0.5)
| Rhesus | Application of generalized matching law
| [41] |
| 14 | Cocaine (0.1–0.056)
Remifentanil
Methohexital (0.32) | Cocaine (0.1–0.056)
Remifentanil (0.0001–0.00003)
Methohexital (0.32) | Rhesus | Application of generalized matching law | [42] |
| 15 | Cocaine (0.05–1.5) | Cocaine (0.1–1.5)
Methylphenidate (0.075–0.07)
Diethylpropion (0.5–1)
| Rhesus | Effect of various pharmacological and environmental manipulations | [31] |
| 16 | Cocaine (0.05–1.5) | Methylphenidate (0.075–0.7) | Rhesus | Drug versus drug preference | [10] |
| 17 | Cocaine (0.05–0.2) | d,l-Cathinone (0.05–0.2) | Rhesus | Drug versus drug preference | [47] |
| 18 | Cocaine (0–0.1) | Procaine (0.4–1.6) | Rhesus | Drug versus drug preference | [46] |
| 19 | Cocaine (0.01–0.03) | PTT (0.01–0.03) | Rhesus | Drug versus drug preference | [50] |
| 20 | Cocaine (0.01–0.03) | Remifentanil (0.0001–0.0003) | Rhesus | Behavioral economic analysis of choice | [51] |
| 21 | Cocaine (0.03) | Remifentanil (0.00003) | Rhesus | Effect of chronic morphine administration and withdrawal on drug choice | [78] |
| 22 | Cocaine (0.267 or 0.8) | Nicotine (8–75)
| Rat | Drug versus drug preference | [49] |
| 23 | Cocaine (0.4) | Heroin (0.025) | Rat | Effect of home cage environment | [52] |
| 24 | Secobarbital (18–100 mg)
Chlordiazepoxide (5–20 mg) | Saline
Secobarbital
| Rhesus | Effect of dependence and withdrawal | [29] |
| 25 | Cocaine (0.1) | Cocaine (0.01–0.56)
Remifentanil (0.00003–0.003)
Cocaine + Remifentanil
| Rhesus | Effect of drug mixtures on drug choice | [69] |
| 26 | Cocaine (0.038–3) | Heroin (0.025–0.05)
Cocaine + Heroin
| Rat | Effect of drug mixtures on drug choice | [68] |
| 27 | Cocaine (0.8) | Cocaine (0.267–2.4)
SKF82958 (0.003–0.03)
(+)-PHNO (0.001–0.01)
SKF82958 + (+)-PHNO
| Rat | Effect of drug mixtures on drug choice | [48] |
| 28 | Cocaine (0.05–0.1) | Cocaine (0.05–0.1) + histamine (0.00037–0.0005) | Rhesus | Effect of punishment (IV histamine) delay on drug choice
| [73] |
| 29 | Cocaine (0.3) | Food pellet | Rhesus | First study of cocaine versus food choice | [53] |
| 30 | Cocaine (0.03–1) | Food pellet | Rhesus | Effect of response requirement
| [58] |
| 31 | Cocaine (0.03–1) | Food pellet | Rhesus | Effect of food availability conditions
| [59] |
| 32 | Cocaine (0.05–0.4) | Food pellet | Rhesus | Behavioral economic analysis of choice | [99] |
| 33 | Cocaine (0.05–0.2) | Food pellet | Rhesus | Behavioral economic analysis of choice | [100] |
| 34 | Cocaine (0.025–0.05) | Food pellet | Rhesus | Application of generalized matching law | [101] |
| 35 | Cocaine (0.0032–0.32) | Food pellet | Rhesus | Effect of dose and cocaine pretreatment | [54] |
| 36 | Cocaine (0.33) | Food pellet or water | Rat | Effect of alternative reinforcer on drug choice | [63] |
| 37 | Cocaine (0.25) | Glucose/Saccharin solution | Rat | Effect of alternative reinforcer on drug choice | [62] |
| 38 | Cocaine (0.25–1.5) | Saccharin or Sucrose | Rat | Effect of sweet solutions on drug choice | [65] |
| 39 | Cocaine (0.1–0.3) | Food pellet | Rhesus | Effect of chronic lithium treatment | [86] |
| 40 | Cocaine (0.05–0.3) | Food pellet | Rhesus | Effect of chronic antipsychotic treatment | [85] |
| 41 | Cocaine (0.0032–0.1) | Food pellet | Rhesus | Effect of monoamine releasers with varying selectivity for dopamine versus serotonin | [17] |
| 42 | Cocaine (0.0032–0.1) | Food pellet | Rhesus | Effect of various pharmacological and environmental manipulations | [55] |
| 43 | Cocaine (0.0032–0.1) | Food pellet | Rhesus | Effect of chronic kappa opioid treatment | [84] |
| 44 | Cocaine (0.0032–0.1) | Food pellet | Rhesus | Effect of chronic methadone treatment | [18] |
| 45 | Cocaine (0.003–0.1) | Food pellet
10% Sweet Condensed milk | Rhesus
Squirrel monkey | Effect of acute and chronic aripiprazole treatment | [93] |
| 46 | Cocaine (0.003–0.03) | Food pellet | Cynomolgus
| Effect of 8-OH-DPAT treatment | [83] |
| 47 | Cocaine (0-1) | Ensure liquid food | Rat | Effect of acute and chronic aripiprazole treatment | [61] |
| | Cocaine (0-1) | Ensure liquid food | Rat | Effect of amphetamine treatment and environmental manipulations
| [81] |
| 48 | Cocaine (0.25) | Saccharin | Rat | Effect of diazepam treatment | [82] |
| 49 | Cocaine (0.0032–0.1) | Food pellet | Rhesus | Effect of punishment (IV histamine) | [72] |
| 50 | Cocaine (0.0032–0.1) | Food pellet | Rhesus | Effect of exposure to and withdrawal from extended cocaine access | [80] |
| 51 | Cocaine (0.003–0.03) | Food pellet | Cynomolgus
| Effect of social hierarchy | [91] |
| 52 | Cocaine (0.003–0.1) | Food pellet | Cynomolgus | Effect of social hierarchy and environmental stimuli
| [56] |
| 53 | Cocaine (0.03–0.56)
Procaine (1–10)
| Food pellet | Rhesus | Effect of drug type and food reinforcer magnitude | [57] |
| 54 | Cocaine (0.003–0.3)
Methylphenidate (0.003–0.1)
Amphetamine (0.003–0.1)
Atomoxetine (0.01–0.3)
Desipramine (0.3–1)
| Food pellet | Rhesus | Effects of drug type on drug versus food choice | [102] |
| 55 | Cocaine (0.0032–0.1)
Heroin (0.0032–0.1)
Cocaine + Heroin | Food pellet | Rhesus | Effects of drug mixtures on drug choice | [67] |
| 56 | Cocaine (0–0.1) | Food pellet | Rhesus | Reinstatement of cocaine choice by dopaminergic compounds
| [103] |
| 57 | Heroin (0.1) | Food | Baboon | Effect of economic conditions
| [60] |
| 58 | Heroin (0.055–0.83) | Food pellet ± Heroin (0.055–0.83) | Baboon | Various pharmacological and environmental manipulations | [66] |
| 59 | Heroin (0.32–0.96) | Food pellet | Baboon | Effect of methadone, naloxone treatment | [74] |
| 60 | Heroin (0.32 or 1) | Food pellet | Baboon | Effect of morphine, naloxone, secobarbital | [75] |
| 61 | Heroin (0.0032–0.1)
Heroin + SNC80 | Food pellet | Rhesus | Effect of drug mixtures on drug choice | [70] |
| 62 | Heroin (0.0032–0.1) | Food pellet | Rhesus | Effect of methadone, buprenorphine, naloxone treatment in nondependent and opioid-dependent monkeys
| [76] |
| 63 | Heroin (0.0032–0.1) | Food pellet | Rhesus | Effect of morphine, amphetamine, clonidine, antalarmin, norbinaltorphimine treatment in opioid-dependent monkeys | [79] |
| 64 | MDMA (0.03–0.3) | Food pellet | Rhesus | Effect of ambient temperature | [92] |
| 65 | MDMA (0.03–0.3) | Food pellet | Rhesus | Effect of thyroid hormone levels | [94] |
| 66 | Methamphetamine (0.06) | Food pellet | Rat | Drug versus food preference | [64]
|
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