Table of Contents Author Guidelines Submit a Manuscript
Anesthesiology Research and Practice
Volume 2011, Article ID 165874, 8 pages
Research Article

The Effect of a Hyperdynamic Circulation on Tissue Doppler Values: A Simulation in Young Adults during Exercise

1Department of Pharmacology, University of Melbourne, Level 8, Medical Building, 3010 Carlton, Australia
2Department of Anaesthesia and Pain Management, The Royal Melbourne Hospital, 3050 Melbourne, Australia
3Department of Cardiology, The First Affiliated Hospital of Kunming Medical University, Yunnan Province 650034, China
4Department of Cardiothoracic Surgery, The Royal Melbourne Hospital, 3050 Melbourne, Australia

Received 5 October 2010; Accepted 15 January 2011

Academic Editor: Christoph K. Hofer

Copyright © 2011 Colin F. Royse et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Left ventricular tissue Doppler imaging (TDI) velocities are used to monitor systolic and diastolic function, but it is not known how these may change in a hyperdynamic circulation, as often occurs in anesthesia and critical care medicine. Twenty-six healthy young volunteers were recruited and left ventricular systolic and diastolic tissue Doppler velocities measured at rest, light exercise, strenuous exercise, and recovery (10 minutes after exercise). At rest, TDI velocities significantly decreased from base to apex ( 𝑃 < . 0 0 1 ). Within basal, mid, and apical sections, systolic and diastolic peak velocities differed between segments ( 𝑃 < . 0 5 ), except for systolic middle ( 𝑃 = . 0 9 4 ) and late diastolic apical velocities ( 𝑃 = . 2 5 7 ). Basal septal velocities differed from basal lateral, for systolic ( 𝑃 = . 0 4 1 ) but not diastolic peak values. Inferobasal radial values differed from basal lateral values for both systolic and diastolic velocities ( 𝑃 < . 0 5 ). Both systolic and diastolic TDI velocities increased significantly in all segments in a proportionate manner with a hyperdynamic circulation.