Immunomodulatory Effects of Anesthetics during Thoracic Surgery

Table 2

Changes in alveolar IL-8, TNF-α, MDA, and SOD in both groups.

Time points	Group I (Propofol) No. = 25				Group II (Isoflurane) No. = 25
	IL-8 (pg/mL)	TNF-α (pg/mL)	MDA (μmoL/litre)	SOD (U/g Hb)	IL-8 (pg/mL)	TNF-α (pg/mL)	MDA (μmoL/litre)	SOD (U/g Hb)
𝑇0	331 (68)	4.7 (1.9)	0.31 (0.04)	98 (14)	328 (65)	5.0 (2.1)	0.29 (0.06)	96 (12)
𝑇1	787 (74)^†*	36.5 (15.1)^†*	0.08 (0.03)^†*	119 (16)^†*	522 (80)^‡*	21.1 (8.1)^‡*	0.43 (0.09)^‡*	100 (15)*
𝑇2	954 (78)^†*	50.4 (20.4)^†*	0.07 (0.02)^†*	117 (15)^†*	601 (82)^‡*	26.3 (12.4^)‡*	0.46 (0.13)^‡*	101 (14)*

IL-8: interleukin-8; TNF-α: tumour necrosis factor-𝛼; MDA: malondialdehyde; SOD: superoxide dismutase. Data are expressed as mean (SD). ^†𝑃<0.05 within the propofol group, ^‡𝑃<0.05 within the isoflurane group, *𝑃<0.05 between both groups.