Immunomodulatory Effects of Anesthetics during Thoracic Surgery

Table 3

Changes in plasma IL-8, TNF-α, MDA, and SOD in both groups.

Time points	Group I (Propofol) No. = 25				Group II (Isoflurane) No. = 25
	IL-8 (pg/mL)	TNF-α (pg/mL)	MDA (μmoL/litre)	SOD (U/g Hb)	IL-8 (pg/mL)	TNF-α (pg/mL)	MDA (μmoL/litre)	SOD (U/g Hb)
𝑇0	2.5 (0.4)	21 (5)	2.8 (1.2)	532 (54)	2.4 (0.5)	23 (6)	2.7 (1.0)	538 (62)
𝑇1	16 (2.4)^†*	95 (24)^†*	1.8 (0.5)^†*	644 (58)^†*	9.1 (1.4)^‡*	77 (19)^‡*	4.1 (1.6)^‡*	542 (70)*
𝑇2	13.4 (2.9)^†*	293 (53)^†*	1.7 (0.4)^†*	640 (57)^†*	7.9 (2.4)^‡*	151 (41)^‡*	4.4 (1.3)^‡*	543 (69)*

IL-8: interleukin-8; TNF-α: tumour necrosis factor-α; MDA: malondialdehyde; SOD: superoxide dismutase. Data are expressed as mean (SD). ^†𝑃<0.05 within the propofol group, ^‡𝑃<0.05 within the isoflurane group, *𝑃<0.05 between both groups.