Review Article

Current Concepts in the Management of Postoperative Nausea and Vomiting

Table 2

Antiemetic doses and timing for administration in adults.

DrugDoseTiming

Ondansetron4–8 mg IVAt end of surgery
Dolasetron12.5 mg/IVAt end of surgery
Granisetron0.35–1mg IVAt end of surgery
Tropisetron5 mg IVAt end of surgery
Dexamethasone5–10 mg IVAt induction
Droperidol0.625–1.25 mg IVAt end of surgery
Ephedrine1–2 mg/KG IVAt end of surgery
Prochlorperazine5–10 mg IVAt end of surgery
Promethazine12.5–25 mg IVAt end of surgery
ScopolamineTransdermal patchApplied prior evening or 4 hr before end of surgery

Based on the original article by Gan et al. [52].