Research Article

Lasting Developmental Effects of Neonatal Fentanyl Exposure in Preweanling Rats

Figure 6

Performance in the elevated plus maze: (a) percent time in the open arms was significantly increased in fentanyl rats compared to saline rats (* ) or unoperated controls (§ ), suggesting that neonatal fentanyl exposure reduces some measures of anxiety-like behavior on the elevated plus maze; (b) and (c) represent the number of open arm and the number of closed arm entries, respectively, showing no significant differences between groups. Values represent mean and 95% confidence interval for mean.
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(a)
180124.fig.006b
(b)
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(c)