Clinical Study

Dexmedetomidine versus Remifentanil for Sedation during Awake Fiberoptic Intubation

Table 1

Advantages and disadvantages of remifentanil versus dexmedetomidine.

RemifentanilAdvantagesDisadvantages
SedativeHemodynamic instability
AnalgesicRespiratory depression
Ultra-short acting
Anti-tussive
Reversed by naloxone

DexmedetomidineAdvantagesDisadvantages
SedativeHigh cost ($80 for 200 mcg vial)*
AnalgesicNeed for slow controlled bolus
Xerostomia followed by titrated infusion
Minimal respiratory depression Limited availability in European countries

*Cost at Memorial Hermann Hospital, Houston, TX.