The Association of Postcardiac Surgery Acute Kidney Injury with Intraoperative Systolic Blood Pressure Hypotension
Table 2
Characterizations of blood pressure variability and association with percent delta creatinine.
BP descriptor
P value for BP measure
Model r-square
Hemodynamic variable median (25th–75th percentile) (units are indicated in the first column)
AUC for 95/135 (mm Hg·min)
0.33
0.058
930 (424–2707)
AUC < 95 (mm Hg·min)
0.36
0.058
447 (130–1584)
AUC > 135 (mm Hg·min)
0.72
0.058
207 (71–443)
AUC for 20% (mm Hg·min-above + below)
0.08
0.059
2268 (702–5698)
AUC for 20% below baseline
0.09
0.059
2117 (509–5542)
AUC for 20% above baseline
0.74
0.058
5.07 (0–74)
Number of total incursions
0.31
0.058
13 (9–17)
Number of incursions >135
0.25
0.058
4 (2–6)
Number of incursions <95
0.57
0.058
9 (5–13)
Cumulative minutes >135 or <95 mm Hg (min)
0.42
0.058
17.7 (3.1–6.8)
Minutes >135 or <95 mm Hg per incident (min)
0.29
0.061
4.8 (3.3–7.8)
Cumulative minutes >135 mm Hg (min)
0.39
0.058
14 (6–25)
Minutes >135 mm Hg per incursion (min)
0.84
0.061
3.7 (2.3–5.7)
Cumulative minutes <95 mm Hg (min)
0.55
0.058
49 (18–116)
Minutes <95 mm Hg per incursion (min)
0.27
0.058
4.9 (2.8–10.8)
Mean incursion nadir <95 mm Hg
0.01
0.060
13 (9–17)
Mean incursion peak >135 mm Hg
0.56
0.058
21 (12–31)
Percent change below baseline (to minimum)
0.006
0.065
53 (62–43)
Percent change above baseline (to maximum)
0.51
0.063
24 (9–48)
All models are adjusted for aprotinin use, age, chf, previous mi, baseline creatinine, bypass time, diabetes, weight, valve surgery, gender, and pulse pressure. P values for these covariates are not shown.
