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Anesthesiology Research and Practice
Volume 2013, Article ID 750901, 10 pages
http://dx.doi.org/10.1155/2013/750901
Review Article

Copper and Anesthesia: Clinical Relevance and Management of Copper Related Disorders

1Department of Anesthesia, Queen Elizabeth II Jubilee Hospital, Locked Bag 2 ARCHERFIELD, Coopers Plains, QLD 4108, Australia
2Department of Chemistry, Saint Francis University, P.O. Box 600, Loretto, PA 15940-0600, USA

Received 28 February 2013; Accepted 16 April 2013

Academic Editor: Kouichiro Minami

Copyright © 2013 Adrian Langley and Charles T. Dameron. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Recent research has implicated abnormal copper homeostasis in the underlying pathophysiology of several clinically important disorders, some of which may be encountered by the anesthetist in daily clinical practice. The purpose of this narrative review is to summarize the physiology and pharmacology of copper, the clinical implications of abnormal copper metabolism, and the subsequent influence of altered copper homeostasis on anesthetic management.