Review Article

Perioperative Intravenous Patient-Controlled Analgesic Efficacy of Morphine with Combined Nefopam and Parecoxib versus Parecoxib in Gynecologic Surgery: A Randomized, Double-Blind Study

Table 1

Demographic data.

Nefopam (N = 36)Control (N = 35) value

Age (years)41.9 ± 9.642.9 ± 8.10.667
Weight (kg)59.8 ± 10.761.9 ± 10.20.412
Height (m)1.6 ± 0.11.6 ± 0.10.226
BMI (kg.m−2)24.5 ± 4.424.8 ± 3.90.777

ASA
 I13 (36.1%)12 (34.3%)0.872
 II23 (63.9%)23 (65.7%)

Diagnosis
 Adenomyosis3 (8.3%)11 (31.4%)0.014
 Cervix cancer1 (2.8%)0 (0%)1.000
 Endometrial cyst2 (5.6%)0 (0%)0.493
 Endometrium cancer1 (2.8%)0 (0%)1.000
 Endometrium hyperplasia0 (0%)1 (2.9%)0.493
 Myoma uteri24 (66.7%)18 (51.4%)0.192
 Ovarian mass5 (13.9%)5 (14.3%)1.000

Type of operation
 TAH36 (100.0%)35 (100.0%)0.117
 TAH with BSO26 (72.2%)19 (54.3%)
Operation time (min)164.2 ± 53.8162.3 ± 62.90.893
Blood loss (mL)344.4 ± 383.9437.7 ± 508.70.385

Type of wound incision
 Midline12 (33.3%)8 (22.9%)0.327
 Pfannenstiel24 (66.7%)27 (77.1%)
Incision length (cm)11.9 ± 2.911.8 ± 2.80.898

Data are represented as mean ± standard deviation or number (%) where appropriate. Abbreviations: TAH, total abdominal hysterectomy; BSO, bilateral salpingo-oophorectomy.