Perioperative Intravenous Patient-Controlled Analgesic Efficacy of Morphine with Combined Nefopam and Parecoxib versus Parecoxib in Gynecologic Surgery: A Randomized, Double-Blind Study
Table 1
Demographic data.
Nefopam (N = 36)
Control (N = 35)
value
Age (years)
41.9 ± 9.6
42.9 ± 8.1
0.667
Weight (kg)
59.8 ± 10.7
61.9 ± 10.2
0.412
Height (m)
1.6 ± 0.1
1.6 ± 0.1
0.226
BMI (kg.m−2)
24.5 ± 4.4
24.8 ± 3.9
0.777
ASA
I
13 (36.1%)
12 (34.3%)
0.872
II
23 (63.9%)
23 (65.7%)
Diagnosis
Adenomyosis
3 (8.3%)
11 (31.4%)
0.014
Cervix cancer
1 (2.8%)
0 (0%)
1.000
Endometrial cyst
2 (5.6%)
0 (0%)
0.493
Endometrium cancer
1 (2.8%)
0 (0%)
1.000
Endometrium hyperplasia
0 (0%)
1 (2.9%)
0.493
Myoma uteri
24 (66.7%)
18 (51.4%)
0.192
Ovarian mass
5 (13.9%)
5 (14.3%)
1.000
Type of operation
TAH
36 (100.0%)
35 (100.0%)
0.117
TAH with BSO
26 (72.2%)
19 (54.3%)
—
Operation time (min)
164.2 ± 53.8
162.3 ± 62.9
0.893
Blood loss (mL)
344.4 ± 383.9
437.7 ± 508.7
0.385
Type of wound incision
Midline
12 (33.3%)
8 (22.9%)
0.327
Pfannenstiel
24 (66.7%)
27 (77.1%)
Incision length (cm)
11.9 ± 2.9
11.8 ± 2.8
0.898
Data are represented as mean ± standard deviation or number (%) where appropriate. Abbreviations: TAH, total abdominal hysterectomy; BSO, bilateral salpingo-oophorectomy.