A Randomized Controlled Trial for Prevention of Postspinal Anesthesia Shivering in Gynecological Surgeries: Mirtazapine vs. Dexamethasone
Table 2
Incidence, grades, and treatment of postspinal anesthesia shivering among the studied groups.
Time points
M group (n = 100)
D group (n = 100)
C group (n = 100)
value
Incidence of shivering; n, %
41 (41%) a
62 (62%) b
91 (91%) c
#<0.001
Grade; n, %
(i) 0
59 (59%) a
38 (38%) b
9 (9%) c
#<0.001
(ii) I
25(25%) a
31 (31%) a
17 (17%) a
(iii) II
10 (10%) a
19 (19%) a
43 (43%) b
(iv) III
6 (6%) a
12 (12%) a
31 (31%) b
Patients with clinically significant shivering (Grade ≥2); n, %
16 (16%) a
31 (31%) b
74 (74%) c
#<0.001
Onset of shivering (min)
51.3 ± 5.2 a
32.8 ± 3.5 b
16.0 ± 5.4 c
^<0.001
Dose of meperidine (mg)
25.1 ± 1.2 a
31.3 ± 4.7b
36.1 ± 3.5 c
^<0.001
Response rate after administration of 1st dose of meperidine; n, %
16 (100%) a
22 (71%) b
41 (55.4%) b
#0.002
Recurrence; n, %
0 (0.0%) a
9 (29%) b
33 (44.6%) b
#0.002
Data were presented as numbers and percent. #Chi square test and ^ANOVA test. Labels (a, b, c) denote homogenous groups depending on post hoc Bonferroni test. Statistically significant. M group: mirtazapine group; D group: dexamethasone group; C group: control group.
