Research Article

Single Dose Intravenous Paracetamol versus Placebo in Postorthognathic Surgery Pain: A Randomized Clinical Trial

Table 2

Pain scores, morphine consumption, and patients’ satisfaction according to the treatment groups.

CharacteristicsStudy group (n = 31)Control group (n = 31) value

VAS pain scale, mean ± SD
 1 hour1.2 ± 1.45.1 ± 2.1<0.001
 4 hour0.8 ± 1.34.2 ± 1.4<0.001
 8 hour1.3 ± 1.43.5 ± 1.1<0.001
 12 hour1.3 ± 1.42.9 ± 1.3<0.001
 16-hour1.0 ± 1.12.3 ± 1.6<0.001
 20-hour0.7 ± 0.92.3 ± 1.4<0.001
 24-hour0.6 ± 0.91.8 ± 1.3<0.001
Morphine consumption (mcg/kg), mean ± SD45.1 ± 21.2136.5 ± 49.9<0.001
Satisfaction (0–5), mean ± SD4.7 ± 0.54.1 ± 0.7<0.001

Differences between treatment groups were tested using MANOVA. A significant difference after Bonferroni multiple testing correction is indicated in bold.