Probenecid decreases the incidence of renal toxicity by cidofovir, might for tenofovir [28] Acyclovir increases serum concentrations of tenofovir Tenofovir increases DDI levels [29]
MRP-4
Inhibition of MRP-4: probenecid dipyridamole NSAIDs [30]
Acyclovir increase serum concentrations of tenofovir NSAIDs associated with tenofovir nephrotoxicity [30, 31]
Cidofovir, acyclovir, valaciclovir, ganciclovir, and valganciclovir
MRP-2
Ritonavir is transported by MRP-2
Ritonavir increases tenofovir concentration and has been associated with tenofovir nephrotoxicity