AIDS Research and Treatment / 2011 / Article / Tab 2

Case Report

Graves' Disease as a Manifestation of Immune Reconstitution in HIV-Infected Individuals after Initiation of Highly Active Antiretroviral Therapy

Table 2

Thyroid workup and management (FT4: free T4, TSH: thyroid stimulating hormone, TPO-Ab: thyroid peroxidase antibody, TBG-Ab: thyroglobulin antibody, PTU: propylthiouracil).

No.Thyroid Work UpTime till symptomsSymptomsPrevious thyroid conditionHCV coinfectionTreatmentHistory of autoimmune disease

(1)FT4: 7.43 ng/dL
TSH < 0.01 MIU/mL TPO-Ab: 46.7 IU/mL
TBG-Ab < 1 IU/mL
44 monthsThyromegaly, lid lag, weight loss, alopecia, diarrhea, and tachycardiaNoNoMethimazole I-131 radioablationNo

(2)TSH < 0.01 MIU/mL FT4: 3.3 ng/dL
Diffuse uptake on thyroid scan
53 monthsTremor, weight loss, exophthalmos, and thyromegalyNoNoMethimazole atenololNo

(3)TSH < 0.004 MIU/mL
T4: 12.2 ng/dL
TBG-Ab: 40 IU/mL
31 monthsWeight loss, tremor, exophthalmos, lid lag, and fatigueNoNoPTU metoprololNo

(4)Not available19 monthsTremors, weight loss, loss of appetite, thyromegaly, and exophthalmosNoNomethimazole metoprololNo

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