Research Article

Utilization Patterns and Projected Demand of Antiretroviral Drugs in Low- and Middle-Income Countries

Table 2

Demand for antiretroviral medicines for the linear projection with fast and slower phase-out of stavudine, 2008–2012 (person-years of antiretroviral therapy) (millions).

Year
20082009201020112012

MoleculeReportedaFast d4T phase-outaSlower d4T phase-outaDifference between scenariosFast d4T phase-outaSlower d4T phase-outaDifference between scenariosFast d4T phase-outaSlower d4T phase-outaDifference between scenariosFast d4T phase-outaSlower d4T phase-outaDifference between scenarios

d4T1.922.122.235%2.002.4120%1.682.4847%1.182.43105%
ZDV1.261.671.60−4%2.151.92−11%2.682.23−17%3.262.56−22%
3TC3.234.034.00−1%4.734.70−1%5.405.36−1%6.065.96−2%
NVP2.002.342.30−2%2.702.61−3%3.002.85−5%3.263.00−8%
EFV1.151.721.720%2.142.161%2.592.642%3.083.142%
ABC0.050.060.0712%0.060.0946%0.050.11115%0.040.14297%
ddI0.080.090.109%0.090.1235%0.070.1495%0.030.15360%
IDV0.010.010.0136%0.010.02142%0.010.03345%0.010.05750%
LPV0.180.220.220%0.280.281%0.340.353%0.410.434%
TDF0.210.540.50−8%1.020.89−13%1.631.38−15%2.371.99−16%
FTC0.100.250.24−2%0.380.36−4%0.550.51−6%0.740.69−7%
NFV0.010.010.01−6%0.010.01−20%0.010.00−45%0.000.00−100%
RTV0.160.220.222%0.280.296%0.340.3810%0.410.4815%
SQV0.000.000.0069%0.000.01228%0.000.01448%0.000.02730%
ATV0.030.030.038%0.030.0428%0.040.0654%0.040.0888%

aUnits are millions of person-years of antiretroviral therapy.