Research Article

CD8+ T-Cell Responses before and after Structured Treatment Interruption in Ugandan Adults Who Initiated ART with CD4+ T Cells <200 Cell/μL: The DART Trial STI Substudy

Figure 3

Magnitudes of CD8+ T-cell responses associated with STI. This figure compares the median magnitudes of HIV-induced CD8+ T-cell IFN-γ responses in (a) STI and CT participants after one cycle of STI or matching time on CT. Bars represent medians, while error bars represent interquartile ranges. The shaded areas represent HIV proteins that induced significantly lower magnitudes of CD8+IFN-γ + than Gag or Nef. (c) illustrates the median change in magnitudes of HIV-specific IFN-γ responses after one cycle of STI or matching time on CT. Horizontal bars represent medians.
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(a)
875028.fig.003b
(b)
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(c)