Patient Characteristics Associated with HCV Treatment Adherence, Treatment Completion, and Sustained Virologic Response in HIV Coinfected Patients

Table 1

Patient characteristics and HCV treatment adherence.

Variable	Good adherence (𝑁=49)	Poor adherence (𝑁=19)	P-value
Demographics
Male gender	94%	95%	0.89
African-American	27%	42%	0.21
Mean age (years)	48.5	47.1	0.59
Any college education	61%	47%	0.30
Employed	31%	42%	0.37
In a relationship	23%	26%	0.77
HIV Disease characteristics
Mean CD4 count (cells/mm^3)	522	560	0.50
Mean log10 HIV RNA (copies/ml)	2.16	2.37	0.48
HIV RNA ≤400	83%	72%	0.35
HCV Disease characteristics
HCV genotype 1 or 4	69%	74%	0.73
Mean log10 HCV RNA (copies/ml)	6.04	6.22	0.46
HCV RNA <800,000	42%	44%	0.92
Psychosocial functioning
Depressed	35%	50%	0.26
Any psychiatric disorder*	38%	67%	0.04
Any drinking problem	14%	21%	0.50
Any illicit drug use	14%	11%	0.68
Any missed appointments (past 6 months)	31%	32%	0.94
Good ART adherence^1	60%	54%	0.69

* 𝑃<0.05.
¹Good adherence is defined as 100% adherence.