Research Article
Patient Characteristics Associated with HCV Treatment Adherence, Treatment Completion, and Sustained Virologic Response in HIV Coinfected Patients
Table 2
Patient characteristics and HCV treatment completion.
| Variable | Treatment complete () | Treatment discontinued () | P-value |
| Demographics | Male gender | 93% | 96% | 0.59 | African American | 30% | 31% | 0.96 | Mean age (years) | 47.2 | 50.9 | 0.12 | Any college education | 58% | 58% | 0.97 | Employed | 37% | 31% | 0.59 | In a relationship | 24% | 19% | 0.66 |
| HIV Disease characteristics | Mean CD4 count (cells/mm3) | 507 | 534 | 0.65 | Mean log10 HIV RNA (copies/ml) | 2.29 | 2.17 | 0.63 | HIV RNA ≤400 | 79% | 77% | 0.81 |
| HCV Disease characteristics | HCV genotype 1 or 4 | 65% | 81% | 0.17 | Mean log10 HCV RNA (copies/ml) | 6.08 | 6.24 | 0.39 | HCV RNA <800,000 | 45% | 38% | 0.57 |
| Psychosocial functioning | Depressive disorder | 36% | 50% | 0.26 | Any psychiatric disorder | 40% | 58% | 0.15 | Any drinking problem | 12% | 23% | 0.21 | Any illicit drug use | 12% | 15% | 0.65 | Any missed clinic appointments (past 6 months) | 35% | 23% | 0.30 | Good HCV treatment | 79% | 55% | 0.04 |
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. 1Good adherence is defined as 100% adherence.
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