Patient Characteristics Associated with HCV Treatment Adherence, Treatment Completion, and Sustained Virologic Response in HIV Coinfected Patients

Table 3

Patient characteristics and sustained virologic response (SVR) to HCV treatment.

Variable	SVR (𝑁=32)	No SVR (𝑁=33)	P-value
Demographics
Male gender	94%	97%	0.54
African-American	25%	30%	0.63
Mean age (years)*	45.9	51.7	0.01
Any college education	53%	58%	0.72
Employed	44%	27%	0.17
In a relationship	13%	27%	0.15
HIV Disease characteristics
Mean CD4 count (cells/mm)	486	522	0.51
Mean log10 HIV RNA (copies/ml)	2.43	2.09	0.20
HIV RNA ≤400	76%	81%	0.61
HCV Disease characteristics
HCV genotype 1 or 4	63%	79%	0.15
Mean log10 HCV RNA (copies/ml)	6.01	6.31	0.14
HCV RNA <800,000	46%	33%	0.31
Psychosocial functioning
Depressive disorder	41%	47%	0.67
Any psychiatric disorder	43%	56%	0.30
Any drinking problem	16%	18%	0.78
Any illicit drug use	16%	12%	0.68
Any missed clinic appointments	31%	27%	0.72
Good HCV treatment adherence^∗1	81%	59%	0.05

^∗𝑃=0.05
¹Good adherence is defined as 100% adherence.