Research Article

The Changing Epidemiology of Oropharyngeal Candidiasis in Patients with HIV/AIDS in the Era of Antiretroviral Therapy

Table 1

Patient demographics of 215 subjects by colonization status.

Colonized
Yes ( 𝑁 = 1 7 6 )No ( 𝑁 = 3 9 ) 𝑃 -value

Age, mean (SD)42.7 (8.9)42.3 (8.5)0.7791
Male, 𝑛 (%)157 (89.7)34 (85)0.3932
White, 𝑛 (%)54 (30.9)7 (17.5)0.1343
Non-Hispanic, 𝑛 (%)82 (46.9)11 (27.5)0.0262
Years since diagnosis of HIV/AIDS, mean (SD)8.4 (6.9)6.4 (6.5)0.0864
Diabetic, 𝑛 (%)15 (8.5)2 (5)0.7453
History of Smoking, 𝑛 (%)127 (72.1)24 (60)0.1172
Uses dentures, 𝑛 (%)42 (23.8)3 (7.5)0.0183
Thrush present, 𝑛 (%)59 (33.5)0 (0)<0.0013
History of esophageal Candida, 𝑛 (%)8 (4.5)3 (7.5)0.4333
Decreased susceptibility to fluconazole, 𝑛 (%)16 (9.1)0 (0)0.0472
On ART therapy, 𝑛 (%)117 (66.4)31 (79.5)0.1452
History of antifungal use, 𝑛 (%)59 (33.5)20 (50)0.0542
CD4 count, mean (SD)102.8 (80.3)84.9 (67.8)0.2834
Viral load, mean (SD)607142.5 (3442957.1)103189.7 (161265.9)0.5884

1 𝐹 test.
2Pearson's 𝜒 2 test.
3Fisher's exact test.
4Kruskal-Wallis test.