AIDS Research and Treatment / 2012 / Article / Tab 1

Research Article

Reduced Central Memory CD4+ T Cells and Increased T-Cell Activation Characterise Treatment-Naive Patients Newly Diagnosed at Late Stage of HIV Infection

Table 1

(a) Demographic and immunovirological characteristics of study population. (b) Peripheral T lymphocyte immune phenotypes of study population.
(a)

CharacteristicsPatients ( )

Age, years*37 (31–46)
Gender, male°225 (82)
Risk group°
 Homosexual152 (55)
 Heterosexual111 (40)
 IDUs10 (4)
 Other2 (1)
Migrants°73 (26)
HCV coinfection°16 (6)
Calendar year of presentation°
 200785 (31)
 200861 (22)
 200961 (22)
 201061 (22)
 January–March 20117 (3)
AIDS presenters°49 (18)
HIV-RNA log10 cp/mL*4.37 (2.78–5.16)
CD4+ T cells/ L*396 (234–555)

(b)

T-cells immunophenotypesPatients ( )

CD4 T cells %*22 (14–30)
CD8 T cells %*51 (42–60)
CD4+CD127+ cells %*12 (7–20)
CD8+CD127+ cells %*11 (8–17)
CD4+CD95+ cells %*2 (1–4)
CD8+CD95+ cells %*2 (1–4)
CD8+CD38+ cells %*6 (3–12)
CD8+CD38+CD45R0+ cells %*12 (7–20)

Data are presented as *median, (interquartile range, IQR) and °absolute number, (%). IDUs: injection drug users; migrants: people who were born outside the European community (including people from Eastern Europe, Africa, Asia, and Latin America); HCV: hepatitis C virus.

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