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Author | Year | Country | Scoring system | Percent also with EPTB | Validation |
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Shah et al. [12] | 1992 | India | Modified Kenneth Jones | Looked at “primary complex” (just pulmonary) versus “progressive primary complex” (pulmonary plus LAD) | Not analyzed, just used in inclusion criteria |
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Migliori et al. [30] | 1992 | Uganda | Migliori | All pulmonary | Gastric aspirate: sens 96.8%, spec 92.2%, PPV 68.2%, NPV 99.4%. Response to treatment: sens 62.5%, 94.1%, PPV 57.7%, NPV 95.1% |
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Beyers et al. [35] | 1994 | South Africa | Modified 1883 WHO criteria | All pulmonary—excluded extrapulmonary tuberculosis without lung involvement | Not evaluated |
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Salazar et al. [32] | 2001 | Peru | Migliori | All pts had PTB, 21/135 had EPTB as well: lymphadenopathy, intestinal-intraperitoneal TB, intra-abdominal lymphadenopathy, miliary disease, meningitis, and optic involvement. 3 with EPTB did not meet criteria for PTB | Sens 92% (Migliori) versus 80% (Peru). 3/3 Peru criteria had 73% PPV |
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Sant'Anna et al. [25] | 2004 | Brazil | Brazil Ministry of Health | 82% very likely, 16% possible, 2.4% unlikely | All pulmonary plus 5 pts with assoc extrapulmonary TB |
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Sant'Anna et al. [24] | 2006 | Brazil | Brazil Ministry of Health | Cut off ≥40: sens 58% and spec 98% but missed 42% of confirmed PTB. Cut off ≥30: sens 89% and spec 86% | Pulmonary |
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Oberhelmen et al. [14] | 2006 | Peru | Stegen-Toledo | Not analyzed, just used in inclusion criteria | Pulmonary |
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Marais et al. [26] | 2006 | South Africa | New | Children ≥3 and HIV uninfected: sens 82.3%, spec 90.2%, PPV 82.3%. Children <3 and HIV uninfected: sens 51.8%, spec 92.5%, PPV 90.1%. HIV infected: sens 56.2%, spec 61.8%, PPV 61.9% | Focused on pulmonary TB only |
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Viani et al. [8] | 2008 | Mexico | Stegen-Toledo | Looked retrospectively: 10/13 highly probable, 2/13 probable, 1/13 suspicious | 100% pulmonary, 54% also had disseminated |
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Pedrozo et al. [23] | 2009 | Brazil | Brazil Ministry of Health | Analyzed scoring system by looking at median scores of various groups: median score of 3a and 3b sig. higher than 1 and 2, median score also was higher than the cut off of 30 | Pulmonary only |
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