Research Article
Imputation of the Date of HIV Seroconversion in a Cohort of Seroprevalent Subjects: Implications for Analysis of Late HIV Diagnosis
Table 1
Years between imputed date of seroconversion and date of HIV diagnosis in the whole cohort (
).
| | Years between imputed date of seroconversion and date of HIV diagnosis | | N | Median (P25–P75) | Mean | |
| Sex | | | | <0.001 | Men | 2854 | 2.90 (1.24–5.40) | 3.66 | | Women | 813 | 2.32 (0.98–4.60) | 3.15 | |
| Age at HIV diagnosis | | | | <0.001 | Up to 20 | 158 | 1.31 (0.49–2.55) | 1.66 | | 21–30 | 1239 | 2.11 (0.86–4.36) | 2.93 | | 31–40 | 1361 | 2.99 (1.32–5.56) | 3.78 | | 41–50 | 599 | 3.67 (1.70–6.05) | 4.25 | | 51–60 | 219 | 4.16 (2.18–6.44) | 4.59 | | Over 60 | 74 | 4.27 (2.22–6.42) | 4.57 | | Not available | 17 | 3.66 (2.04–5.57) | 4.11 | — |
| Transmission category | | | | <0.001 | Injection drug user | 578 | 1.82 (0.59–4.40) | 2.87 | | Men who have sex with men | 1581 | 2.73 (1.25–5.17) | 3.57 | | Heterosexual risk exposure | 1376 | 3.08 (1.38–5.53) | 3.76 | | Other (vertical, transfusions, tattoos, etc.) | 58 | 3.03 (1.33–5.48) | 3.63 | | Don’t know/No answer | 74 | 3.81 (1.83–6.10) | 4.28 | |
| Educational level | | | | 0.790 | No education or less than primary | 257 | 2.88 (1.07–5.20) | 3.46 | | Primary | 1214 | 2.68 (1.09–5.20) | 3.49 | | Secondary completed | 1011 | 2.79 (1.22–5.25) | 3.57 | | University completed | 524 | 2.84 (1.29–5.33) | 3.66 | | Not available | 661 | 2.75 (1.19–5.20) | 3.54 | — |
| Country of origin | | | | 0.011 | Spain | 2512 | 2.57 (1.07–5.06) | 3.42 | | Western Europe | 114 | 2.96 (1.23–5.40) | 3.74 | | Eastern Europe and Russia | 72 | 2.97 (1.46–5.16) | 3.58 | | Sub-Saharan Africa | 246 | 3.54 (1.68–5.88) | 4.04 | | North Africa | 58 | 3.89 (1.77–6.35) | 4.51 | | Latin America | 631 | 3.04 (1.36–5.45) | 3.71 | | Other/not available | 34 | 2.84 (1.46–5.25) | 3.77 | |
| AIDS | | | | <0.001 | Yes | 633 | 4.13 (2.01–6.19) | 4.32 | | No | 3034 | 2.49 (1.09–4.90) | 3.38 | |
| Death | | | | 0.081 | Yes | 86 | 4.08 (1.84–6.12) | 4.25 | | No | 3581 | 2.73 (1.16–5.21) | 3.53 | |
| Total | 3667 | 2.76 (1.17–5.24) | 3.54 | |
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