Table 1: Baseline characteristics of 156 subjects characterized by ACE-I/ARB exposure.

VariableNo ACE-I/ARB (n = 114)ACE-I/ARB (n = 42)P value

Mean age (years) ± standard deviation (SD)50.3 ± 8.653.4 ± 5.50.04
Male gender (%)76 (66.7)31 (73.8)0.40
Black race (%)34 (29.8)20 (47.6)0.04
Hispanic ethnicity (%)67 (58.8)21 (50)0.33
Mean BMI (kg/m2) ± SD25.6 ± 6.227.0 ± 6.80.34
Median HCV RNA (IU/mL) (range) 3.66 106 (600–4.23 107)3.54 106 (600–3.08 107)0.70
Median log10 HCV RNA (range)6.56 (2.78–7.63)6.55 (2.78–7.49)0.70
Undetectable HIV viral load (%)60 (52.6)28 (66.7)0.12
Median HIV viral load* (copies/mL) (range)1.61 104 (58–8.21 105)421 (65–2.11 105)0.03
Median log10 HIV viral load* (range)4.21 (1.76–5.91)2.62 (1.81–5.33)0.03
Median CD4 cell count (cells/mL) (range)372 (11–2193)389 (51–1183)0.31
Alcohol Use (%)37 (32.5)9 (21.4)0.18
Prior HCV Treatment (%)8 (5.1)6 (3.8)0.16
Diagnosis of diabetes (%)13 (11.4)23 (54.8)<0.001
Proteinuria (%)34 (32.1)25 (61)<0.001
Mean hemoglobin A1C (g/dL) ± SD5.37 ± 0.666.15 ± 1.330.03
Significant fibrosis by clinical data (%)32 (28.1)18 (42.9)0.08

*Calculated in those with detectable HIV viral load.