Table of Contents Author Guidelines Submit a Manuscript
AIDS Research and Treatment
Volume 2013, Article ID 819593, 8 pages
http://dx.doi.org/10.1155/2013/819593
Research Article

Feasibility and Field Performance of a Simultaneous Syphilis and HIV Point-of-Care Test Based Screening Strategy in at Risk Populations in Edmonton, Canada

1Alberta Health Services, Edmonton STI Clinic, 3B20 1111 Jasper Avenue, Edmonton, Alberta, Canada T5K 0L4
2Public Health Agency of Canada, 130 Colonnade Road, A.L. 6501H, Ottawa, ON, Canada K1A 0K9
3Provincial Laboratory for Public Health, 8440-112 Street, Edmonton, AB, Canada T6G 2J2

Received 5 June 2013; Accepted 13 November 2013

Academic Editor: Nitika Pant Pai

Copyright © 2013 Joshua Bergman et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. Patrick, T. Wong, and R. Jordan, “Sexually transmitted infections in Canada: recent resurgence threatens national goals,” Canadian Journal of Human Sexuality, vol. 6, pp. 149–146, 2000. View at Google Scholar
  2. Public Health Agency of Canada, “Report on Sexually Transmitted Infections in Canada: 2008,” 2010, http://www.phac-aspc.gc.ca/std-mts/report/sti-its2008/PDF/10-047-STI_report_eng-r1.pdf.
  3. Public Health Agency of Canada, “Syphilis. Canadian Guidelines on Sexually Transmitted Infections,” January 2010, http://www.phac-aspc.gc.ca/std-mts/sti-its/cgsti-ldcits/section-5-10-eng.php.
  4. Government of Alberta, “Syphilis outbreak—cases continue to rise in Alberta,” News Release March 2007, http://www.gov.ab.ca/acn/200703/2114837853E7C-B959-29A4-3A5E50ACA420B304.html.
  5. Government of Alberta, “The Syphilis Outbreak in Alberta. Office of the Chief Medical Officer of Health,” December 2010, http://www.health.alberta.ca/documents/STI-Syphilis-Report-2010.pdf.
  6. J. Gratix, L. Honish, L. Mashinter et al., “Case series descriptive analysis of a primary syphilis outbreak in Edmonton, Alberta, July 2004-April 2006,” Canada Communicable Disease Report, vol. 33, no. 6, pp. 61–67, 2007. View at Google Scholar · View at Scopus
  7. Unpublished data, Alberta Health Services, Edmonton, Alberta, Canada.
  8. Government of Alberta, “Notifiable Sexually Transmitted Infections 2011 Annual Report,” http://www.health.alberta.ca/documents/STI-ND-Annual-Report-2011.pdf.
  9. J. Sexton, G. Garnett, and J.-A. Røttingen, “Metaanalysis and metaregression in interpreting study variability in the impact of sexually transmitted diseases on susceptibility to HIV infection,” Sexually Transmitted Diseases, vol. 32, no. 6, pp. 351–357, 2005. View at Publisher · View at Google Scholar · View at Scopus
  10. J.-A. Røttingen, W. D. Cameron, and G. P. Garnett, “A systematic review of the epidemiologic interactions between classic sexually transmitted diseases and HIV: how much really is known?” Sexually Transmitted Diseases, vol. 28, no. 10, pp. 579–597, 2001. View at Google Scholar · View at Scopus
  11. Government of Alberta, “HIV and AIDS in Alberta 2011 Annual Report,” November 2012, http://www.health.alberta.ca/documents/STI-HIV-AIDS-Report-2011.pdf.
  12. A. Singh, S. Hill, and S. Shafran, “Non-return rates for HIV testing: results of a 3-month retrospective review at an STD clinic in 1999,” Canada Communicable Disease Report, vol. 26, no. 18, pp. 152–155, 2000. View at Google Scholar · View at Scopus
  13. S. Campbell and Y. Fedoriw, “HIV testing near the patient: changing the face of HIV testing,” Clinics in Laboratory Medicine, vol. 29, no. 3, pp. 491–501, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. P. Ward, “Near-patient testing will improve the control of sexually transmitted infections: the arguments in favour,” Sexually Transmitted Infections, vol. 82, no. 6, pp. 506–508, 2006. View at Publisher · View at Google Scholar · View at Scopus
  15. R. W. Peeling, D. Mabey, A. Herring, and E. W. Hook III, “Why do we need quality-assured diagnostic tests for sexually transmitted infections?” Nature Reviews Microbiology, vol. 4, no. 12, pp. 909–921, 2006. View at Publisher · View at Google Scholar · View at Scopus
  16. R. W. Peeling and H. Ye, “Diagnostic tools for preventing and managing maternal and congenital syphilis: an overview,” Bulletin of the World Health Organization, vol. 82, no. 6, pp. 439–446, 2004. View at Google Scholar · View at Scopus
  17. D. C. Mabey, K. A. Sollis, H. A. Kelly et al., “Point-of-care tests to strengthen health systems and save newborn lives: the case of syphilis,” PLOS Medicine, vol. 9, no. 6, Article ID e1001233, 2012. View at Publisher · View at Google Scholar
  18. B. M. Branson, “State of the art for diagnosis of HIV infection,” Clinical Infectious Diseases, vol. 45, no. 4, pp. S221–S225, 2007. View at Publisher · View at Google Scholar · View at Scopus
  19. J. H. Nichols, “Point of Care Testing,” Clinics in Laboratory Medicine, vol. 27, no. 4, pp. 893–908, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. L. Greer and G. D. Wendel Jr., “Rapid Diagnostic Methods in Sexually Transmitted Infections,” Infectious Disease Clinics of North America, vol. 22, no. 4, pp. 601–617, 2008. View at Publisher · View at Google Scholar · View at Scopus
  21. J. D. Tucker, J. Bu, L. B. Brown, Y.-P. Yin, X.-S. Chen, and M. S. Cohen, “Accelerating worldwide syphilis screening through rapid testing: a systematic review,” The Lancet Infectious Diseases, vol. 10, no. 6, pp. 381–386, 2010. View at Publisher · View at Google Scholar · View at Scopus
  22. D. Mabey, R. W. Peeling, R. Ballard et al., “Prospective, multi-centre clinic-based evaluation of four rapid diagnostic tests for syphilis,” Sexually Transmitted Infections, vol. 82, no. 5, pp. v13–v16, 2006. View at Publisher · View at Google Scholar · View at Scopus
  23. B. E. Lee, S. Plitt, J. Fenton, J. K. Preiksaitis, and A. E. Singh, “Rapid HIV tests in acute care settings in an area of low HIV prevalence in Canada,” Journal of Virological Methods, vol. 172, no. 1-2, pp. 66–71, 2011. View at Publisher · View at Google Scholar · View at Scopus
  24. Government of Alberta, “Alberta Treatment Guidelines for Sexually Transmitted Infections (STI) in Adolescents and Adults,” 2012, http://www.health.alberta.ca/documents/STI-Treatment-Guidelines-2012.pdf.
  25. Standard Diagnostics, Inc., “SD Bioline Syphilis 3.0 Test Product Insert,” March 2010, http://www.standardia.com/html_e/mn03/mn03_01_00.asp?intId=28.
  26. Alberta Health Services—The Provincial Laboratory for Public Health, The Division of Medical Microbiology—University of Alberta, “Guide to Services,” 2013, http://www.provlab.ab.ca/guide-to-services.pdf.
  27. BioLytical Laboratories, “INSTI HIV-1/HIV-2 Antibody Test Product Insert,” 2007, http://www.biolytical.com/insti_doc/CEInsert.pdf.
  28. Alberta Health Services, “The Provincial Laboratory for Public Health. Laboratory Bulletin: HIV, HCV, and HBV serology testing change,” June 2011, http://www.provlab.ab.ca/LabBulletin2011/HIV_HCV_HBV_Serology_Testing_Change_Bulletin_June_9_2011.pdf.
  29. F. Spielberg, B. M. Branson, G. M. Goldbaum et al., “Choosing HIV counseling and testing strategies for outreach settings: a randomized trial,” Journal of Acquired Immune Deficiency Syndromes, vol. 38, no. 3, pp. 348–355, 2005. View at Google Scholar · View at Scopus
  30. C. G. Beckwith, S. Atunah-Jay, J. Cohen et al., “Feasibility and acceptability of rapid HIV testing in jail,” AIDS Patient Care and STDs, vol. 21, no. 1, pp. 41–47, 2007. View at Publisher · View at Google Scholar · View at Scopus
  31. L. F. Haynes, J. E. Korte, B. E. Holmes et al., “HIV rapid testing in substance abuse treatment: implementation following a clinical trial,” Evaluation and Program Planning, vol. 34, no. 4, pp. 399–406, 2011. View at Publisher · View at Google Scholar · View at Scopus
  32. D. L. Pugatch, B. G. Levesque, M. A. Lally et al., “HIV testing among young adults and older adolescents in the setting of acute substance abuse treatment,” Journal of Acquired Immune Deficiency Syndromes, vol. 27, no. 2, pp. 135–142, 2001. View at Google Scholar · View at Scopus
  33. K. E. Bowles, H. A. Clark, E. Tai et al., “Implementing rapid HIV testing in outreach and community settings: results from an advancing HIV prevention demonstration project conducted in seven U.S. cities,” Public Health Reports, vol. 123, no. 3, pp. 78–85, 2008. View at Google Scholar · View at Scopus
  34. M. Siedner, V. Zapitz, M. Ishida, R. De La Roca, and J. D. Klausner, “Performance of rapid syphilis tests in venous and fingerstick whole blood specimens,” Sexually Transmitted Diseases, vol. 31, no. 9, pp. 557–560, 2004. View at Publisher · View at Google Scholar · View at Scopus
  35. M. Hernández-Trejo, B. Hernández-Prado, F. Uribe-Salas, L. Juárez-Figueroa, and C. J. Conde-González, “Maternal and congenital syphilis in two Mexican hospitals: evaluation of a rapid diagnostic test,” Revista de Investigacion Clinica, vol. 58, no. 2, pp. 119–125, 2006. View at Google Scholar · View at Scopus
  36. L. Juárez-Figueroa, F. Uribe-Salas, S. García-Cisneros, M. Olamendi-Portugal, and C. J. Conde-Glez, “Evaluation of a rapid strip and a particle agglutination tests for syphilis diagnosis,” Diagnostic Microbiology and Infectious Disease, vol. 59, no. 2, pp. 123–126, 2007. View at Publisher · View at Google Scholar · View at Scopus
  37. A. R. Castro, J. Esfandiari, S. Kumar et al., “Novel point-of-care test for simultaneous detection of nontreponemal and treponemal antibodies in patients with syphilis,” Journal of Clinical Microbiology, vol. 48, no. 12, pp. 4615–4619, 2010. View at Publisher · View at Google Scholar · View at Scopus
  38. Y. Jafari, R. W. Peeling, S. Shivkumar, C. Claessens, L. Joseph, and N. P. Pai, “Are Treponema pallidum specific rapid and point-of-care tests for syphilis accurate enough for screening in resource limited settings? Evidence from a meta-analysis,” PLoS ONE, vol. 8, no. 2, 2013. View at Publisher · View at Google Scholar
  39. A. Herring, R. Ballard, D. Mabey, and R. W. Peeling, “Evaluation of rapid diagnostic tests: syphilis,” Nature Reviews Microbiology, vol. 4, no. 12, pp. S33–S40, 2006. View at Publisher · View at Google Scholar · View at Scopus
  40. Y.-P. Yin, X.-C. Chen, W.-H. Wei et al., “A dual point-of-care test shows good performance in simultaneously detecting nontreponemal and treponemal antibodies in patients with syphilis: a multisite evaluation study in China,” Clinical Infectious Diseases, vol. 56, pp. 659–665, 2013. View at Google Scholar
  41. World Health Organization, “The use of rapid syphilis tests,” 2006, http://whqlibdoc.who.int/hq/2006/TDR_SDI_06.1_eng.pdf.
  42. A. E. Singh, K. Sutherland, B. Lee, J. L. Robinson, and T. Wong, “Resurgence of early congenital syphilis in Alberta,” CMAJ, vol. 177, no. 1, pp. 33–36, 2007. View at Publisher · View at Google Scholar · View at Scopus
  43. Public Health Agency of Canada, “Summary: Estimates of HIV Prevalence and Incidence in Canada,” 2011, http://www.phac-aspc.gc.ca/aids-sida/publication/survreport/assets/pdf/estimat2011-eng.pdf.