Establishment of Normal Reference Intervals for CD3⁺, CD4⁺, CD8⁺, and CD4⁺ to CD8⁺ Ratio of T Lymphocytes in HIV Negative Adults from University of Gondar Hospital, North West Ethiopia

Table 4

Gender based 95% reference interval of HIV negative adults visited VCT, University of Gondar Hospital, Ethiopia, 2013, as compared with other countries.

Parameter	Current study	Ethiopia	CAR	Nigeria	India	Switzerland
Males
CD3^+/L	611–2974	759–2742	NA	NA	NA	521–1772
CD4^+/L	265–1685; 355–1213^∗	391–1145	380–1617	351–1455	383–1347	336–1126
CD8^+/L	206–1733	249–1933	267–1545	155–863	NA	125–780
CD4 : CD8 ratio/L	0.4–2.8	0.41–2.57	0.34–1.88	0.7–5.1	NA	0.9–6.0
Females
CD3^+/L	828–2824	741–2329	NA	NA	NA	595–1861
CD4^+/L	387–1411; 470–1298^∗	386–1355	386–1454	383–1654	448–1593	314–1270
CD8^+/L	241–1667	258–1301	226–1225	133–919	NA	147–836
CD4 : CD8 ratio/L	0.6–2.50	0.52–2.60	0.6–2.27	0.8–5.8	NA	1.0–4.9
References in numbers		[16]	[17]	[11]	[18]	[19]

User’s guideline values, NA = not available.