Prevalence of and Risk Factors for Lipoatrophy in Patients with HIV Infection in Nigeria
Table 4
Demographic, anthropometric, and body composition of lipoatrophy in the study participants.
Characteristic
Lipoatrophy = 75
No lipoatrophy = 213
value
Demographic
Age (years)
41.7 ± 8.8
38.9 ± 8.6
0.02*
Gender
Male (, %)
48 (41.4%)
68 (58.6%)
0.0001*
Female (, %)
27 (15.7%)
145 (84.3%)
Anthropometric
BMI, male (kg/m2)
23.1 ± 3.3
26.5 ± 3.8
0.0001*
BMI, female (kg/m2)
21.2 ± 2.1
25.8 ± 5.0
0.0001*
WC, male (cm)
82.1 ± 9.3
92.6 ± 10.7
0.0001*
WC, female (cm)
77.0 ± 6.2
85.9 ± 11.5
0.0001
HC, male (cm)
93.2 ± 6.3
103.2 ± 8.5
0.0001*
HC, female (cm)
90.8 ± 5.1
102.2 ± 10.4
0.0001*
WHR, male
0.88 ± 0.08
0.90 ± 0.06
0.49
WHR, female
0.85 ± 0.06
0.84 ± 0.06
0.25
Median triceps (mm), male
5.0 (3.3–7.2)
9.3 (5.0–12.7)
0.0001*
Median (IQR) triceps, female (mm)
8.7 (6.0–11.0)
18.0 (11.0–25.0)
0.0001*
Median SST, male (mm)
23.7 (17.2–30.3)
34.7 (25.0–48.7)
0.0001*
Median SST, female (mm)
27.0 (23.3–36.7)
51.0 (38.7–119.7)
0.0001*
Median % of body fat, male
14.1 (13.0–16.7)
23.6 (17.9–28.0)
0.0001*
Median % of body fat, female
25.1 (19.9–27.7)
37.2 (31.1–55.5)
0.0001*
Median % of skeletal muscle mass, male
41.0 (38.9–42.6)
35.7 (33.0–38.4)
0.0001*
Median % skeletal muscle mass, female
31.5 (24.9–35.1)
26.4 (24.1–28.8)
0.0001*
Median (IQR) known duration of HIV infection (months)
30.0 (8.0–49.0)
20 (7.5–30.0)
0.06
CD4 count (cells/mm3)
>500
13 (15.9)
69 (84.1)
0.04*
200–500
50 (29.4)
120 (70.6)
<200
12 (33.3)
24 (66.7)
Median (IQR)
309 (242–409)
356 (253–539)
0.03*
Viral load (copies/mL)
<200
45 (31.5)
98 (68.5)
0.05
≥200
30 (20.7)
115 (79.3)
Total number on HAART
48 (33.1%)
97 (67.9%)
0.01*
Median (IQR) duration of HAART (months)
32.0 (15.5–49.0)
26.0 (16.0–38.0)
0.29
HAART regimen
Stavudine based
22 (45.8%)
26 (54.2%)
0.04*
Zidovudine based
19 (30.6%)
43 (69.4%)
Tenofovir based
7 (20.0%)
28 (80.0%)
Statistically significant; BMI: body mass index, WC: waist circumference, HC: hip circumference, and WHR: waist-to-hip ratio. All values are mean ± SD unless stated.
